Publications
Heath S.L; Guseman A.J; Gronenborn A.M; Horne W.S.; “Effects of Site-specific dehydration and isomerization on the structure and stability of GB1” Accepted at Protein Science
Zhao, H.; Wu, H.; Guseman, A.J.; Abeykoon, D.; Camara, C.; Dalal, Y.; Fushman, D.; Papoian, G.; “The Principles of Histone Folding in Archaea and Eukarya” Accepted PLOS Computational Biology
Guseman, A.J.; Murphy, L.; Nambulli, S.K.; Roy. C.N.; Martinez. D.R.; Yang D.T.; Bhinderwala, F.; Vergara, S.; Schaefer, A.; Baric, R.S.; Ambrose, Z.; Duprex, W.P.; Gronenborn A.M.; “Targeting Spike Glycans as an Inhibitory Mechanism of SARS-CoV2 Viral Entry” Proceedings of the National Academies of Sciences 120(38):e2301518120
Zhu, W.; Guseman A.J.; Bhinderwala, F.; Lu, M.; Su, X.; Gronenborn, A.M. “Visualizing Proteins in Mammalian Cells by 19F NMR” Angewandte Chemie International Edition (In Press e202201097 1-5).
Speer, S.L.; Zheng, W.; Jiang, X.; Chu, I.; Guseman, A.J.; Liu, M.; Pielak, G.J; Li, C.; (2021) “The intracellular environment tunes protein-protein interactions” Proceedings of the National Academies of Sciences 118:11
Guseman, A.J.; Whitley, M.J.; Gonzalez, J.J.; Rathi, N.; Ambarian, M; Gronenborn, A.M.; (2020) “Assessing the Structures and Interactions of yD-Crystallin Deamidation Variants” Structure 29, 284-291
Krone, K.W.*; Albanese K.I.*; Leighton, G.O.; He, C.Q.; Lee, G.Y.; Garcia-Borras, M.; Guseman, A.J.; Williams D.C.J; Houk, K.N.; Brustad, E.M.; Waters, M.L.; “Thermodynamic Consequences of Tyr to Trp Mutations in the Cation-π-Mediated Binding of Trimethyllysine by the HP1 Chromodomain” Chemical Science 11(14) 3495-3500
Guseman, A.J.; Pielak, G.J.; (2020) Chapter 12: Protein Stability and weak intracellular interactions: In-cell NMR Spectroscopy: From Molecular Sciences to Cell Biology Shirakawa, M. Döstch, V. and Ito, Yutaka. (The Royal Society of Chemistry) pp 188-206
Free, M.E.; Stember, KG.; Hess, H.J.; McInnis, E.A.; Lardinois, O.; Hogan, S.L.; Hu, Y.; Mendoza, C.; Le, A.K.; Guseman A.J.; Pilkinton, M.A.; Bortone, D.S.; Cowens, K.; Sidney, F.; Karosiene, E.; Peters, B.; James, E.; Kwok, W.W.; Vincent, B.G.; Mallal, S.A.; Jennette, C.J.; Ciavatta, D.J.; Falk, R.J. (2019) “Restricted Myeloperoxidase Epitopes Drive the Adaptive Immune Response in ANCA Vasculitis” Journal of Autoimmunity 106:102306
Speer, S.L.; Guseman, A.J; Patteson, J.B.; Ehrmann B.M.;Pielak, G.J.; (2019) “Controlling and quantifying protein concentration in Escherichia coli cells” Protein Science 28:1307-1311
Guseman, A.J.; Gronenborn A.M.; (2019) “Isomerization, an Achilles Heel to Long-Lived Proteins” Journal of Biological Chemistry 294:7556-7557
Piszkiewicz, S.P.; Gunn, K.H.; Warmuth, O.; Propst, A.; Mehta, A.; Nguyen. K.H.; Kuhlman, E.; Guseman, A.J.; Stadmiller. S.S.; Boothby T.C.; Neher, S.B.; Pielak, G.J.; (2019) “Protecting Activity of Desiccated Enzymes” Protein Science 28:5 941-951
Guseman, A.J.;Perez Goncalves, G.M.; Speer, S.L.; Young, G.B.; Pielak G.J.; (2018) “Protein Shape Modulates Crowding Effects” Proceedings of the National Academies of Sciences 115 (43):10965-10970
Guseman, A.J.*; Speer, S.L.*; Perez Goncalves, G.M.; Pielak G.J.; (2018) “Surface-charge modulates protein-protein interactions in physiologically relevant environments” Biochemistry 57:1681-1684.
Stadmiller, S.S.; Gorensk-Benitez, A.H; Guseman, A.J.;Pielak, G.J.; (2017) “Osmotic-Shock Induced Protein Destabilization and its Reversal by Glycine Betaine” Journal of Molecular Biology Accepted doi: 10.1016/j.jmb.2017.03.001
Guseman, A.J.; Pielak, G.J.; (2017) “Cosolute and Crowding Effects on a Side-By-Side Protein Dimer” Biochemistry 56 (7):971-976 DOI:10.1021/acs.biochem.6b01251
Guseman, A.J.; Miller, K.; Kunkle, G.; Dively, G.J.; Pettis, J.S.; Evans, J.D.; vanEngelsdorp, D.; Hawthorne, D.J.; (2016) “Multi-Drug Resistance Transporters and a Mechanism-Based Strategy for Assessing Risks of Pesticide Combinations on Honey Bees” PLoS ONE 11(2): e0148242. doi:10.1371/journal.pone.014824
Cohen, R.D.; Guseman, A.J.;Pielak, G.J.; (2015) “Intracellular pH modulates quinary structure” Protein Science 24 (11):1748-1755
Zhao, H.; Wu, H.; Guseman, A.J.; Abeykoon, D.; Camara, C.; Dalal, Y.; Fushman, D.; Papoian, G.; “The Principles of Histone Folding in Archaea and Eukarya” Accepted PLOS Computational Biology
Guseman, A.J.; Murphy, L.; Nambulli, S.K.; Roy. C.N.; Martinez. D.R.; Yang D.T.; Bhinderwala, F.; Vergara, S.; Schaefer, A.; Baric, R.S.; Ambrose, Z.; Duprex, W.P.; Gronenborn A.M.; “Targeting Spike Glycans as an Inhibitory Mechanism of SARS-CoV2 Viral Entry” Proceedings of the National Academies of Sciences 120(38):e2301518120
Zhu, W.; Guseman A.J.; Bhinderwala, F.; Lu, M.; Su, X.; Gronenborn, A.M. “Visualizing Proteins in Mammalian Cells by 19F NMR” Angewandte Chemie International Edition (In Press e202201097 1-5).
Speer, S.L.; Zheng, W.; Jiang, X.; Chu, I.; Guseman, A.J.; Liu, M.; Pielak, G.J; Li, C.; (2021) “The intracellular environment tunes protein-protein interactions” Proceedings of the National Academies of Sciences 118:11
Guseman, A.J.; Whitley, M.J.; Gonzalez, J.J.; Rathi, N.; Ambarian, M; Gronenborn, A.M.; (2020) “Assessing the Structures and Interactions of yD-Crystallin Deamidation Variants” Structure 29, 284-291
Krone, K.W.*; Albanese K.I.*; Leighton, G.O.; He, C.Q.; Lee, G.Y.; Garcia-Borras, M.; Guseman, A.J.; Williams D.C.J; Houk, K.N.; Brustad, E.M.; Waters, M.L.; “Thermodynamic Consequences of Tyr to Trp Mutations in the Cation-π-Mediated Binding of Trimethyllysine by the HP1 Chromodomain” Chemical Science 11(14) 3495-3500
Guseman, A.J.; Pielak, G.J.; (2020) Chapter 12: Protein Stability and weak intracellular interactions: In-cell NMR Spectroscopy: From Molecular Sciences to Cell Biology Shirakawa, M. Döstch, V. and Ito, Yutaka. (The Royal Society of Chemistry) pp 188-206
Free, M.E.; Stember, KG.; Hess, H.J.; McInnis, E.A.; Lardinois, O.; Hogan, S.L.; Hu, Y.; Mendoza, C.; Le, A.K.; Guseman A.J.; Pilkinton, M.A.; Bortone, D.S.; Cowens, K.; Sidney, F.; Karosiene, E.; Peters, B.; James, E.; Kwok, W.W.; Vincent, B.G.; Mallal, S.A.; Jennette, C.J.; Ciavatta, D.J.; Falk, R.J. (2019) “Restricted Myeloperoxidase Epitopes Drive the Adaptive Immune Response in ANCA Vasculitis” Journal of Autoimmunity 106:102306
Speer, S.L.; Guseman, A.J; Patteson, J.B.; Ehrmann B.M.;Pielak, G.J.; (2019) “Controlling and quantifying protein concentration in Escherichia coli cells” Protein Science 28:1307-1311
Guseman, A.J.; Gronenborn A.M.; (2019) “Isomerization, an Achilles Heel to Long-Lived Proteins” Journal of Biological Chemistry 294:7556-7557
Piszkiewicz, S.P.; Gunn, K.H.; Warmuth, O.; Propst, A.; Mehta, A.; Nguyen. K.H.; Kuhlman, E.; Guseman, A.J.; Stadmiller. S.S.; Boothby T.C.; Neher, S.B.; Pielak, G.J.; (2019) “Protecting Activity of Desiccated Enzymes” Protein Science 28:5 941-951
Guseman, A.J.;Perez Goncalves, G.M.; Speer, S.L.; Young, G.B.; Pielak G.J.; (2018) “Protein Shape Modulates Crowding Effects” Proceedings of the National Academies of Sciences 115 (43):10965-10970
Guseman, A.J.*; Speer, S.L.*; Perez Goncalves, G.M.; Pielak G.J.; (2018) “Surface-charge modulates protein-protein interactions in physiologically relevant environments” Biochemistry 57:1681-1684.
Stadmiller, S.S.; Gorensk-Benitez, A.H; Guseman, A.J.;Pielak, G.J.; (2017) “Osmotic-Shock Induced Protein Destabilization and its Reversal by Glycine Betaine” Journal of Molecular Biology Accepted doi: 10.1016/j.jmb.2017.03.001
Guseman, A.J.; Pielak, G.J.; (2017) “Cosolute and Crowding Effects on a Side-By-Side Protein Dimer” Biochemistry 56 (7):971-976 DOI:10.1021/acs.biochem.6b01251
Guseman, A.J.; Miller, K.; Kunkle, G.; Dively, G.J.; Pettis, J.S.; Evans, J.D.; vanEngelsdorp, D.; Hawthorne, D.J.; (2016) “Multi-Drug Resistance Transporters and a Mechanism-Based Strategy for Assessing Risks of Pesticide Combinations on Honey Bees” PLoS ONE 11(2): e0148242. doi:10.1371/journal.pone.014824
Cohen, R.D.; Guseman, A.J.;Pielak, G.J.; (2015) “Intracellular pH modulates quinary structure” Protein Science 24 (11):1748-1755